International Journal of Medicine and Biomedical Sciences <p><strong>ABOUT</strong></p> <p>International Journal of Medicine &amp; Biomedical Sciences (IJMBioS) is an open access, peer-reviewed, quarterly published journal that encompasses all fundamental and molecular aspects of medical and biomedical sciences. It publishes original research papers, review papers, case studies, short communications, letter to the editors in all novel and innovative aspects of health, disease and environment encompassing medicine and biomedical sciences. </p> <p>We aim to bring relevant findings and message that advances our understanding of medical and biomedical sciences to a wide international audience using health, disease and techniques interrelated with it.</p> <p>The following areas are covered in the Journal:</p> <p>&gt; Molecular Biology &gt; Bioinformatics &gt; Integrative Medicine <br />&gt; Microbiology &gt; Biochemistry &gt; Internal Medicine<br />&gt; Biotechnology &gt; Biologics &gt; Herbal Medicine<br />&gt; Health and Disease &gt; Pharmacy &gt; Occupational Health<br />&gt; Epidemiology &gt; Nursing &gt; Treatment Protocols </p> <p>Scientific contributions from relevant Researchers, Clinical Practitioners, Health Professionals and Research Students under ethical and journal guidelines are appreciated. The major objective of this publication is to promote/ advance science through encouraging the researchers to publish and make the scientific information available to all in the most easily accessible form.</p> <p>The Journal uses the Open Journal System (OJS) of PKP. </p> en-US <p>IJMBioS follows the following Terms and License of the manuscript under <a href="">Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)</a> where Author and Journal are can Share — copy and redistribute the material in any medium or format and Adapt — remix, transform, and build upon the material, and it is Non-Commercial. </p> (Dr. Bishnu Prasad Marasini) (Dr. Prerok Regmi) Sat, 30 Apr 2022 00:00:00 +0000 OJS 60 Acute Acromioclavicular Dislocations Treated with Kirschner wire and Polyester suture at B.P Koirala Institute of Health Sciences: A Retrospective Review of Records. <p><strong>Introduction: </strong><span style="font-weight: 400;">Acromioclavicular (AC) dislocations are relatively rare injuries often seen in athletes who are involved in high-impact sports. The aim of management is to restore the coracoclavicular interspace to maintain stability and prevent chronic pain. Many fixation methods have been described for managing these injuries. To the best of our knowledge, only a few studies have reported regarding the functional outcome of AC joint dislocation using bifocal fixation using K wire and Polyester suture. This study aimed to evaluate the functional outcome of AC joint dislocation managed using a bifocal fixation.</span></p> <p><strong>Method: </strong><span style="font-weight: 400;">This retrospective review of records was conducted between January 19th to January 30th, 2023 after obtaining clearance from the institutional ethics committee. All patients aged between 18-45 years with AC joint dislocations meeting the inclusion criteria were included in the study. The information was recorded in a data extraction form. The University of California, Los Angeles (UCLA) Shoulder Rating Score was evaluated at 6 months follow-up.</span></p> <p><strong>Results: </strong><span style="font-weight: 400;">A total of 34 patients of which there were 30 male and 4 female patients included in this review of records. The average age was 37.69 ± 7.21 years, then the average time of surgery from injury was 2.34 ± 0.5 days and the average duration of surgery was 58.45 ± 5. 14 mins. The mean UCLA shoulder rating scale was 28.26 ± 4.1 for all patients at the final follow-up. Complications like hardware prominence, implant back out, and superficial skin infection were also recorded in the patients.</span></p> <p><strong>Conclusion:</strong><span style="font-weight: 400;"> Bifocal fixation is an acceptable method of fixation for Grade III, IV and V acromioclavicular joint dislocations due to their good functional outcomes, mechanical stability and low cost.However more studies with increased sample size and better designed studies are required to assess their long term outcomes.</span></p> Dr. Jitendar Shah, Dr. Ashish Pandey, Dr. Yam Bahadur Gurung, Dr. Pashupati Chaudhary Copyright (c) 2023 Jitendra Shah, Dr. Ashish Pandey, Dr. Yam Bahadur Gurung, Dr. Pashupati Chaudhary Fri, 17 Feb 2023 00:00:00 +0000 Health related quality of life among people receiving highly active antiretroviral therapy at Bharatpur Hospital, Chitwan, Nepal. <p><strong>Background: </strong><span style="font-weight: 400;">Health-related quality of life (HRQoL) is one of the most important outcome measures among HIV-infected patients receiving highly active antiretroviral therapy (HAART). Likewise, improved quality of life (QoL) is one prominent goal of patient treatment. This study was conducted to investigate the QoL of people living with HIV/AIDS (PLWHA) receiving HAART at the antiretroviral therapy (ART) center of the Bharatpur Hospital in Chitwan, Nepal. </span></p> <p><strong>Methods</strong><span style="font-weight: 400;">: This was a cross-sectional study conducted among 271 PLWHA receiving HAART at the ART center of Bharatpur Hospital in the Chitwan district in April, 2016. Participants were recruited purposely and interviewed with a structured questionnaire. Quality of life was assessed using the World Health Organization Quality of Life HIV- BREF (WHOQOL-HIV-BREF) standard tool. Data was entered to Epi-Info version 3.5.3 and analyzed using SPSS version 21 for windows. A bivariate analysis was fitted to identify factors associated with QoL.</span></p> <p><strong>Result:</strong><span style="font-weight: 400;"> A total of 271 participants, with a mean age of 36.86 (SD = 9.62), were included in the study. This study found that the majority of participants had moderate general QoL, except for the </span><span style="font-weight: 400;">spiritual domain, which contains information about personal beliefs, forgiveness and blame, and concerns about future, death, and dying. Younger patients, religious minorities, literate patients, unmarried patients, those on ART for more than three years, and those who adhered to ART were associated with good general QoL across all domains.</span></p> <p><strong>Conclusion</strong><span style="font-weight: 400;">: The participants’ self-reported HRQoL was generally satisfactory except for Spiritual</span> <span style="font-weight: 400;">domains. Since HIV is a chronic illness, the spiritual need </span><span style="font-weight: 400;">of</span><span style="font-weight: 400;"> patients requires attention, including religious coping or support to find a sense of meaning/support in life, to cope with issues of guilt and shame, and to deal with the grief and bereavement associated with the disease.</span></p> Prativa Adhikari, Dipak Prasad Tiwari, Arun Kumar Joshi, Anil Poudyal, Mamata Sharma, Radha Devi Dhakal, Laxmi Ghimire , Sangita Acharya Sharma Copyright (c) 2022 Prativa Adhikari, Dipak Prasad Tiwari, Arun Kumar Joshi, Anil Poudyal, Mamata Sharma, Radha Devi Dhakal, Laxmi Ghimire , Sangita Acharya Sharma Sat, 30 Apr 2022 00:00:00 +0000